Pirarubicin

Product Name: Pirarubicin
CAS No.: 72496-41-4
Chemical Name: Pirarubicin
Synonyms: Therarubicin;PIRARUBICIN HYDROCHLORIDE;(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione;(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione;CS-702;1609rb;THP-ADM;Pirabucin;Pirarubcin;THEPRUBICIN
CBNumber: CB7315796
Molecular Formula: C32H37NO12
Formula Weight: 627.64
MOL File: 72496-41-4.mol

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Pirarubicin Property

Melting point:: 188-192°C (dec.)
alpha: D25 +175 ±25° (c = 0.2 in CHCl3)
Boiling point:: 834.7±65.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: ethanol: soluble25mg/mL
form: powder
pka: 7.35±0.60(Predicted)
color: Orange to Red
Stability:: Hygroscopic

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
RTECS: QI9296000
Toxicity: LD50 i.v. in mice: 27.8 mg/kg (Umezawa, 1979)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H340May cause genetic defects

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P8624
Product name: Pirarubicin
Purity: ≥95% (HPLC)
Packaging: 10mg
Price: $432
Updated: 2023/06/20

Sigma-Aldrich

Product number: P8624
Product name: Pirarubicin
Purity: ≥95% (HPLC)
Packaging: 25mg
Price: $863
Updated: 2023/06/20

Cayman Chemical

Product number: 28384
Product name: Pirarubicin
Packaging: 10mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 28384
Product name: Pirarubicin
Packaging: 100mg
Price: $638
Updated: 2024/03/01

Cayman Chemical

Product number: 28384
Product name: Pirarubicin
Packaging: 5mg
Price: $44
Updated: 2024/03/01

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Pirarubicin Chemical Properties,Usage,Production

Description

Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.

Chemical Properties

Red Solid

Originator

Meiji Seika (Japan)

Uses

Structural analog of Doxorubicin. Antineoplastic.

Definition

ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline.

brand name

Pinorubicin; Therarubucin

Pirarubicin Preparation Products And Raw materials

Raw materials

Doxorubicin hydrochloride Adriamycin Silica gel Tetrahydropyran

Preparation Products

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Pirarubicin Suppliers

Canada 1 China 213 Europe 4 Germany 2 India 4 Japan 1 Switzerland 1 United Kingdom 6 United States 31 Global 263

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
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Advantage: 70

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
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MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
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AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

Abblis Chemicals LLC

Tel: +1-832-373-8299
Fax: +1-713-664-0347
Email: info@abblis.com
Country: United States
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Target molecule Corp.

Tel: 857-239-0968
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Email: service1@targetmol.com
Country: United States
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Alfa Chemistry

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Email: Info@alfa-chemistry.com
Country: United States
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InvivoChem

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Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
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Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
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BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
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Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
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View Lastest Price from Pirarubicin manufacturers

Hebei Mojin Biotechnology Co., Ltd

Product: Pirarubicin 72496-41-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-07-03

Hebei Guanlang Biotechnology Co., Ltd.

Product: Pirarubicin 72496-41-4
Price: US $1.00/PCS
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2021-05-14

Wuhan Demeikai Biotechnology Co., Ltd

Product: Pirarubicin 72496-41-4
Price: US $10.00/g/Bag
Min. Order: 10g
Purity: 99
Supply Ability: 100KG
Release date: 2021-11-16

72496-41-4, PirarubicinRelated Search:

Doxorubicinone Chrysophanic acid Idarubicin hydrochloride Adriamycin 2-(HYDROXYMETHYL)ANTHRAQUINONE Pirarubicin 1,8-Dihydroxyanthraquinone 1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL 3,4-DIMETHYL-3'-METHOXYBENZOPHENONE 2-METHOXY-4'-METHYLBENZOPHENONE 2-METHOXY-3'-METHYLBENZOPHENONE 14-Hydroxy Carminomycin 2,4-DIMETHYL-3'-METHOXYBENZOPHENONE Carubicin 4-ETHYL-2'-METHOXYBENZOPHENONE L-DaunosamineHCl 3-METHOXY-3'-METHYLBENZOPHENONE ISLANDICIN

THP-ADM

THEPRUBICIN

(8s-cis)-droxyacetyl)-1-methoxy

(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

Tepirubicin

Therarubiein

THP-adriamycin

(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione

5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L- lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-

(8S)-10α-[[3-Amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

(8S,10S)-10α-[[3-Amino-4-O-(tetrahydro-2H-pyran-2-yl)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-hydroxyacetyl-1-methoxy-5,12-naphthacenedione

Pirarubicin(THP-AdriaMycin)

(7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

PIRARUBICIN

PIRARUBICIN HYDROCHLORIDE

CS-702

Pirarubcin

1609rb

4’-o-tetrahydropyranyladriamycin

4’-o-tetrahydropyranyldoxorubicin

5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-4-o-(tetrahydro-2h-pyran-2-y

l)-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hy

Pirarubicin(BICINS)

(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione

Pinorubicin

Therarubicin

Pirabucin

5,12-Naphthacenedione, 10-3-amino-2,3,6-trideoxy-4-O-(2R)-tetrahydro-2H-pyran-2-yl-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-

(8S)-10-[(2S,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione

5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-

Pirarubicin USP/EP/BP

(8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-6-methyl-5-(((R)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Pirarubicin Topoisomerase II inhibitor ab142734

Famoxadone Impurity 14

THP-Doxorubicin

72496-41-4

C32H37NO12

Inhibitors

API

Intermediates & Fine Chemicals

Pharmaceuticals

Chiral Reagents